Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Coughs
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
B2 bradykinin receptorP30411T23714
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00225Belinostat--
BADD_D00227Benazepril0.002686%
BADD_D00228Benazepril hydrochloride--
BADD_D00229Benazeprilat--
BADD_D00230Bendamustine--
BADD_D00231Bendamustine hydrochloride--
BADD_D00233Benicar hydrochlorothiazide--
BADD_D00240Benzonatate0.000274%
BADD_D00246Benzydamine--
BADD_D00254Bepridil--
BADD_D00263Betaxolol--
BADD_D00269Bexarotene--
BADD_D00271Bicalutamide--
BADD_D00274Bimatoprost--
BADD_D00277Bisoprolol--
BADD_D00278Bisoprolol fumarate--
BADD_D00280Bleomycin0.001332%
BADD_D00282Blinatumomab--
BADD_D00283Boceprevir--
BADD_D00284Bortezomib--
BADD_D00285Bosentan0.027497%
BADD_D00286Bosutinib0.005595%
BADD_D00287Bosutinib monohydrate--
BADD_D00289Botulinum neurotoxin a/b immune globulin (human)--
BADD_D00291Brentuximab vedotin--
BADD_D00294Brimonidine--
BADD_D00295Brimonidine tartrate--
BADD_D00296Brinzolamide0.007503%
BADD_D00297Brivaracetam0.000507%
BADD_D00300Bromfenac--
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